The Civil War was very existent in the West. The Confederacy attempted an invasion of Nevada early in the war but it was repulsed at Glorieta Pass and Valverde and the the Union government was worried that local rebels in California would attempt to seize San Francisco. I would argue you'd be less safe out West as the locals tended more towards handling their debates themselves if you know what I mean. Also, the fact that the Federal Government was focusing on a war wasn't lost on the Native Americans and they heated the region back up during the war, even as far North as Minnesota. As for the state enmity question, the "Bleeding Kansas" feuds continued through the war, the only difference being that the two warring parties were now backed by governments. And yes, I consider "Bleeding Kansas" to be the opening skirmishes of the war and a huge arguing point for North and South.